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3tv5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3tv5 is ON HOLD Authors: Rajamohan, F., Marr, E., Reyes, A., Landro, J. A., Anderson, M. D., Corbett, J. W., Dirico, K. J., Harwood, J. H., Tu. M., ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 1== | |
| + | <StructureSection load='3tv5' size='340' side='right'caption='[[3tv5]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3tv5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TV5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RCP:(3R)-1-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4-BIPIPERIDINE'>RCP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tv5 OCA], [https://pdbe.org/3tv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tv5 RCSB], [https://www.ebi.ac.uk/pdbsum/3tv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tv5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACAC_YEAST ACAC_YEAST] Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.<ref>PMID:6108218</ref> <ref>PMID:6103540</ref> <ref>PMID:8943372</ref> <ref>PMID:10757783</ref> <ref>PMID:12730220</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Anderson MD]] | ||
| + | [[Category: Corbett JW]] | ||
| + | [[Category: Dirico KJ]] | ||
| + | [[Category: Harwood JH]] | ||
| + | [[Category: Landro JA]] | ||
| + | [[Category: Marr E]] | ||
| + | [[Category: Rajamohan F]] | ||
| + | [[Category: Reyes A]] | ||
| + | [[Category: Tu M]] | ||
| + | [[Category: Vajdos FF]] | ||
Current revision
Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 1
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