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3t8w
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| - | [[Image:3t8w.jpg|left|200px]] | ||
| - | + | ==A bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases== | |
| - | + | <StructureSection load='3t8w' size='340' side='right'caption='[[3t8w]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3t8w]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T8W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=DGZ:N-((2R,3S,6S,18S,21S)-2-AMINO-18-(4-BENZOYLBENZYL)-21-CARBAMOYL-3-HYDROXY-6-(NAPHTHALEN-2-YLMETHYL)-4,7,16,19-TETRAOXO-1-PHENYL-11,14-DIOXA-5,8,17,20-TETRAAZAPENTACOSAN-25-YL)HEX-5-YNAMIDE'>DGZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t8w OCA], [https://pdbe.org/3t8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t8w RCSB], [https://www.ebi.ac.uk/pdbsum/3t8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t8w ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q8IL11_PLAF7 Q8IL11_PLAF7] | ||
| - | == | + | ==See Also== |
| - | + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | |
| - | + | __TOC__ | |
| - | < | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Plasmodium falciparum 3D7]] | |
| - | + | [[Category: Greebaum DC]] | |
| - | + | [[Category: Klemba M]] | |
| - | + | [[Category: McGowan S]] | |
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| - | [[ | + | |
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| - | [[Category: Plasmodium falciparum]] | + | |
| - | [[Category: Greebaum | + | |
| - | [[Category: Klemba | + | |
| - | [[Category: McGowan | + | |
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Current revision
A bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
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