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3oxt

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[[Image:3oxt.jpg|left|200px]]
 
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==Human cAMP-dependent protein kinase in complex with an inhibitor==
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The line below this paragraph, containing "STRUCTURE_3oxt", creates the "Structure Box" on the page.
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<StructureSection load='3oxt' size='340' side='right'caption='[[3oxt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3oxt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OXT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3SB:(2S)-2-AMINO-N-[(1E)-(2,4-DIHYDROXY-6-METHYLPHENYL)METHYLIDENE]-2-PHENYLETHANEHYDRAZIDE'>3SB</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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{{STRUCTURE_3oxt| PDB=3oxt | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oxt OCA], [https://pdbe.org/3oxt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oxt RCSB], [https://www.ebi.ac.uk/pdbsum/3oxt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oxt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
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===Human cAMP-dependent protein kinase in complex with an inhibitor===
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==See Also==
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*[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3oxt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OXT OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: CAMP-dependent protein kinase]]
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[[Category: Large Structures]]
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[[Category: Heine, A.]]
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[[Category: Heine A]]
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[[Category: Klebe, G.]]
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[[Category: Klebe G]]
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[[Category: Koester, H.]]
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[[Category: Koester H]]
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[[Category: Phosphorylation]]
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[[Category: Transferase]]
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Current revision

Human cAMP-dependent protein kinase in complex with an inhibitor

PDB ID 3oxt

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