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3ozf

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[[Image:3ozf.jpg|left|200px]]
 
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==Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine==
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The line below this paragraph, containing "STRUCTURE_3ozf", creates the "Structure Box" on the page.
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<StructureSection load='3ozf' size='340' side='right'caption='[[3ozf]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ozf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FCR-3/Gambia Plasmodium falciparum FCR-3/Gambia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OZF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.944&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HPA:HYPOXANTHINE'>HPA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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{{STRUCTURE_3ozf| PDB=3ozf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ozf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ozf OCA], [https://pdbe.org/3ozf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ozf RCSB], [https://www.ebi.ac.uk/pdbsum/3ozf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ozf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HGXR_PLAFG HGXR_PLAFG] Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Works with guanine, hypoxanthine and xanthine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
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===Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine===
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3ozf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eukaryota Eukaryota]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OZF OCA].
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[[Category: Large Structures]]
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[[Category: Eukaryota]]
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[[Category: Plasmodium falciparum FCR-3/Gambia]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Hazleton, K Z.]]
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[[Category: Hazleton KZ]]
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[[Category: Ho, M.]]
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[[Category: Ho M]]
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[[Category: Schramm, V L.]]
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[[Category: Schramm VL]]
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[[Category: Hypoxanthine]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine

PDB ID 3ozf

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