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3shw

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[[Image:3shw.jpg|left|200px]]
 
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==Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide==
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The line below this paragraph, containing "STRUCTURE_3shw", creates the "Structure Box" on the page.
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<StructureSection load='3shw' size='340' side='right'caption='[[3shw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3shw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SHW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3shw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3shw OCA], [https://pdbe.org/3shw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3shw RCSB], [https://www.ebi.ac.uk/pdbsum/3shw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3shw ProSAT]</span></td></tr>
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{{STRUCTURE_3shw| PDB=3shw | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>
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===Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide===
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==See Also==
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*[[Connexin 3D structure|Connexin 3D structure]]
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== References ==
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==About this Structure==
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<references/>
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[[3shw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SHW OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chen, J.]]
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[[Category: Large Structures]]
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[[Category: Pan, L.]]
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[[Category: Chen J]]
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[[Category: Yu, H.]]
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[[Category: Pan L]]
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[[Category: Yu, J.]]
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[[Category: Yu H]]
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[[Category: Zhang, M.]]
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[[Category: Yu J]]
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[[Category: Cell adhesion]]
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[[Category: Zhang M]]
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[[Category: Pdz-sh3-guk supramodule]]
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Current revision

Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide

PDB ID 3shw

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