2l4f
From Proteopedia
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| - | [[Image:2l4f.jpg|left|200px]] | ||
| - | + | ==NMR structure of the UBA domain of S. cerevisiae Dcn1 bound to ubiquitin== | |
| - | + | <StructureSection load='2l4f' size='340' side='right'caption='[[2l4f]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2l4f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L4F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4f OCA], [https://pdbe.org/2l4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l4f RCSB], [https://www.ebi.ac.uk/pdbsum/2l4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l4f ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/DCN1_YEAST DCN1_YEAST] Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with HRT1/RBX1 to recruit the Nedd8-charged E2 UBC12 to the cullin component of SCF-type complexes.<ref>PMID:15988528</ref> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | == | + | __TOC__ |
| - | [[2l4f]] is a 1 chain structure with sequence from [ | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Burschowsky | + | [[Category: Burschowsky D]] |
| - | [[Category: Mattle | + | [[Category: Mattle D]] |
| - | [[Category: Peter | + | [[Category: Peter M]] |
| - | [[Category: Rudolf | + | [[Category: Rudolf F]] |
| - | [[Category: Wider | + | [[Category: Wider G]] |
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Current revision
NMR structure of the UBA domain of S. cerevisiae Dcn1 bound to ubiquitin
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