3saq

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[[Image:3saq.png|left|200px]]
 
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==Structure of D13, the scaffolding protein of vaccinia virus==
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The line below this paragraph, containing "STRUCTURE_3saq", creates the "Structure Box" on the page.
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<StructureSection load='3saq' size='340' side='right'caption='[[3saq]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3saq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_WR Vaccinia virus WR]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SAQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.51&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3saq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3saq OCA], [https://pdbe.org/3saq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3saq RCSB], [https://www.ebi.ac.uk/pdbsum/3saq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3saq ProSAT]</span></td></tr>
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{{STRUCTURE_3saq| PDB=3saq | SCENE= }}
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</table>
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== Function ==
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===Structure of D13, the scaffolding protein of vaccinia virus===
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[https://www.uniprot.org/uniprot/D13_VACCW D13_VACCW] Scaffold protein which forms a transitory spherical honeycomb lattice providing curvature and rigidity to the convex membrane of crescent and immature virions (IV). This association occurs concomitantly with viral membrane formation. Targeted by the drug rifampicin, which prevents the formation of this lattice, and hence virus morphogenesis. In the presence of rifampicin, irregularly shaped membranes that lack the honeycomb layer accumulate around areas of electron-dense viroplasm. This layer is lost from virions during maturation from IV to mature virion (MV), through the proteolysis of A17 N-terminus.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_21931553}}, adds the Publication Abstract to the page
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[[Category: Vaccinia virus WR]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21931553 is the PubMed ID number.
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[[Category: Coulibaly F]]
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{{ABSTRACT_PUBMED_21931553}}
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==About this Structure==
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[[3saq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAQ OCA].
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==Reference==
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<ref group="xtra">PMID:021931553</ref><references group="xtra"/>
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[[Category: Vaccinia virus]]
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[[Category: Coulibaly, F.]]
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[[Category: Double-barrel]]
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[[Category: Jelly-roll]]
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[[Category: Rifampicin-resistance protein]]
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[[Category: Scaffolding protein]]
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[[Category: Structural protein]]
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[[Category: Surface of the immature virions and crescent]]
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[[Category: Viral protein]]
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Current revision

Structure of D13, the scaffolding protein of vaccinia virus

PDB ID 3saq

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OCA

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