3s0q

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[[Image:3s0q.png|left|200px]]
 
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==Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis, catalytic site mutant (Cys383Ala) at 1.45 resolution==
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The line below this paragraph, containing "STRUCTURE_3s0q", creates the "Structure Box" on the page.
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<StructureSection load='3s0q' size='340' side='right'caption='[[3s0q]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s0q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S0Q FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s0q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0q OCA], [https://pdbe.org/3s0q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s0q RCSB], [https://www.ebi.ac.uk/pdbsum/3s0q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s0q ProSAT]</span></td></tr>
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{{STRUCTURE_3s0q| PDB=3s0q | SCENE= }}
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</table>
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== Function ==
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===Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis, catalytic site mutant (Cys383Ala) at 1.45 resolution===
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[https://www.uniprot.org/uniprot/RIPA_MYCTU RIPA_MYCTU] Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate. Binds and degrades high-molecular weight peptidoglycan from a number of Actinobacteria; activity is increased in the presence of RpfB and inhibited by PBP1A (ponA1). Required for normal separation of daughter cells after cell division and for cell wall integrity. Required for host cell invasion and intracellular survival in host macrophages.<ref>PMID:16495549</ref> <ref>PMID:17919286</ref> <ref>PMID:18463693</ref> <ref>PMID:20826344</ref> <ref>PMID:21864539</ref>
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== References ==
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<references/>
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21864539 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21864539}}
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==About this Structure==
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[[3s0q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0Q OCA].
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==Reference==
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<ref group="xtra">PMID:021864539</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Both, D.]]
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[[Category: Both D]]
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[[Category: Schneider, G.]]
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[[Category: Schneider G]]
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[[Category: Schnell, R.]]
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[[Category: Schnell R]]
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[[Category: Hydrolase]]
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[[Category: Nlpc/p60 module]]
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[[Category: Peptidoglycan hydrolase]]
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Current revision

Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis, catalytic site mutant (Cys383Ala) at 1.45 resolution

PDB ID 3s0q

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OCA

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