2b6p

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[[Image:2b6p.png|left|200px]]
 
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==X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state==
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The line below this paragraph, containing "STRUCTURE_2b6p", creates the "Structure Box" on the page.
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<StructureSection load='2b6p' size='340' side='right'caption='[[2b6p]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2b6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6p OCA], [https://pdbe.org/2b6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6p RCSB], [https://www.ebi.ac.uk/pdbsum/2b6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6p ProSAT]</span></td></tr>
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{{STRUCTURE_2b6p| PDB=2b6p | SCENE= }}
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</table>
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== Function ==
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===X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state===
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[https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15377788}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15377788 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15377788}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6p ConSurf].
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[[2b6p]] is a 1 chain structure of [[Aquaporin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aquaporin]]
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*[[Aquaporin 3D structures|Aquaporin 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:015377788</ref><ref group="xtra">PMID:016319884</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Cheng, Y.]]
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[[Category: Large Structures]]
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[[Category: Fujiyoshi, Y.]]
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[[Category: Cheng Y]]
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[[Category: Gonen, T.]]
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[[Category: Fujiyoshi Y]]
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[[Category: Harrison, S C.]]
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[[Category: Gonen T]]
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[[Category: Hiroaki, Y.]]
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[[Category: Harrison SC]]
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[[Category: Sliz, P.]]
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[[Category: Hiroaki Y]]
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[[Category: Walz, T.]]
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[[Category: Sliz P]]
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[[Category: Aqp0]]
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[[Category: Walz T]]
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[[Category: Aquaporin]]
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[[Category: Aquaporin-0]]
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[[Category: Lens mip]]
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[[Category: Membrane protein]]
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[[Category: Open water pore]]
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Current revision

X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state

PDB ID 2b6p

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OCA

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