3zst

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[[Image:3zst.png|left|200px]]
 
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==GlgE isoform 1 from Streptomyces coelicolor with alpha-cyclodextrin bound==
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The line below this paragraph, containing "STRUCTURE_3zst", creates the "Structure Box" on the page.
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<StructureSection load='3zst' size='340' side='right'caption='[[3zst]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3zst]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZST FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900015:alpha-cyclodextrin'>PRD_900015</scene></td></tr>
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{{STRUCTURE_3zst| PDB=3zst | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zst OCA], [https://pdbe.org/3zst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zst RCSB], [https://www.ebi.ac.uk/pdbsum/3zst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zst ProSAT]</span></td></tr>
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</table>
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===GLGE ISOFORM 1 FROM STREPTOMYCES COELICOLOR WITH ALPHA-CYCLODEXTRIN BOUND===
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== Function ==
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[https://www.uniprot.org/uniprot/GLGE1_STRCO GLGE1_STRCO] Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Maltooligosaccharides with a degree of polymerization (DP) superior or equal to 4 are efficient acceptors, with DP6 being optimal in the GlgE-catalyzed polymerization with M1P. Is specific for the alpha-anomer of M1P as substrate, since the beta-anomer of M1P gives no activity. Alpha-D-glucose 1-phosphate cannot serve as a donor substrate, but alpha-maltosyl fluoride is an efficient donor in vitro. Exhibits an alpha-retaining catalytic mechanism, with evidence that maltooligosaccharide acceptors are extended at their non-reducing ends. Is also able to catalyze the reverse reaction in vitro, releasing M1P from glycogen or maltoheptaose in the presence of inorganic phosphate. Also catalyzes disproportionation reactions through maltosyl transfer between maltooligosaccharides. Is probably involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.<ref>PMID:21914799</ref>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21914799}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21914799 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21914799}}
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==About this Structure==
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[[3zst]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZST OCA].
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==Reference==
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<ref group="xtra">PMID:021914799</ref><references group="xtra"/>
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[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
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[[Category: Bornemann, S.]]
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[[Category: Bornemann S]]
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[[Category: Bruton, C J.]]
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[[Category: Bruton CJ]]
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[[Category: Chater, K F.]]
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[[Category: Chater KF]]
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[[Category: Fairhurst, S A.]]
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[[Category: Fairhurst SA]]
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[[Category: Field, R A.]]
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[[Category: Field RA]]
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[[Category: Lawson, D M.]]
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[[Category: Lawson DM]]
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[[Category: Nair, A.]]
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[[Category: Nair A]]
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[[Category: Rejzek, M.]]
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[[Category: Rejzek M]]
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[[Category: Stevenson, C E.M.]]
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[[Category: Stevenson CEM]]
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[[Category: Syson, K.]]
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[[Category: Syson K]]
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[[Category: Alpha-glucan biosynthesis]]
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[[Category: Glycoside hydrolase family 13_3]]
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[[Category: Hydrolase]]
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Current revision

GlgE isoform 1 from Streptomyces coelicolor with alpha-cyclodextrin bound

PDB ID 3zst

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