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3q7a
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| - | [[Image:3q7a.png|left|200px]] | ||
| - | + | ==Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123== | |
| - | + | <StructureSection load='3q7a' size='340' side='right'caption='[[3q7a]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3q7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=778:4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE'>778</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7a OCA], [https://pdbe.org/3q7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7a RCSB], [https://www.ebi.ac.uk/pdbsum/3q7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7a ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q55S71_CRYNB Q55S71_CRYNB] | ||
| - | == | + | ==See Also== |
| - | + | *[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Cryptococcus neoformans var. grubii H99]] | |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Beese LS]] | |
| - | + | [[Category: Hast MA]] | |
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| - | [[Category: Cryptococcus neoformans | + | |
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Current revision
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123
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