3poo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==human cAMP-dependent protein kinase in complex with an inhibitor== | |
| + | <StructureSection load='3poo' size='340' side='right'caption='[[3poo]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3poo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3POO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BUD:(2S,3S)-BUTANE-2,3-DIOL'>BUD</scene>, <scene name='pdbligand=S69:N-[(E)-(2,4-DIHYDROXY-6-METHYLPHENYL)METHYLIDENE]-2-(3-METHOXYPHENYL)ACETOHYDRAZIDE'>S69</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3poo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3poo OCA], [https://pdbe.org/3poo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3poo RCSB], [https://www.ebi.ac.uk/pdbsum/3poo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3poo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IPKA_HUMAN IPKA_HUMAN] Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. | ||
| - | + | ==See Also== | |
| - | + | *[[CAMP-dependent protein kinase 3D structures|CAMP-dependent protein kinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Heine A]] | ||
| + | [[Category: Klebe G]] | ||
| + | [[Category: Koester H]] | ||
Current revision
human cAMP-dependent protein kinase in complex with an inhibitor
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