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3tw4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Septin 7 GTPase Domain== | |
| - | + | <StructureSection load='3tw4' size='340' side='right'caption='[[3tw4]], [[Resolution|resolution]] 3.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3tw4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw4 OCA], [https://pdbe.org/3tw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw4 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SEPT7_HUMAN SEPT7_HUMAN] Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.<ref>PMID:17803907</ref> <ref>PMID:18460473</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Alessandro F]] | ||
| + | [[Category: Garratt RC]] | ||
| + | [[Category: Pereira HM]] | ||
| + | [[Category: Serrao VHB]] | ||
| + | [[Category: Thiemann OT]] | ||
Current revision
Crystal Structure of Human Septin 7 GTPase Domain
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