3u2k
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==S. aureus GyrB ATPase domain in complex with a small molecule inhibitor== | |
| + | <StructureSection load='3u2k' size='340' side='right'caption='[[3u2k]], [[Resolution|resolution]] 1.64Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3u2k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U2K FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=087:2-CHLORO-6-(4-{[(3,4-DICHLORO-5-METHYL-1H-PYRROL-2-YL)CARBONYL]AMINO}PIPERIDIN-1-YL)PYRIDINE-4-CARBOXAMIDE'>087</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u2k OCA], [https://pdbe.org/3u2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u2k RCSB], [https://www.ebi.ac.uk/pdbsum/3u2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u2k ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GYRB_STAAU GYRB_STAAU] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.[HAMAP-Rule:MF_01898] | ||
| - | + | ==See Also== | |
| - | + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Boriack-Sjodin PA]] | ||
| + | [[Category: Eakin AE]] | ||
| + | [[Category: Prince DB]] | ||
| + | [[Category: Sherer BA]] | ||
Current revision
S. aureus GyrB ATPase domain in complex with a small molecule inhibitor
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