3u6w
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3u6w is ON HOLD Authors: Koon, N., Baker, E.N., Squire, C.J. Description: Truncated M. tuberculosis LeuA (1-425) complexed with KIV) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Truncated M. tuberculosis LeuA (1-425) complexed with KIV== | |
| + | <StructureSection load='3u6w' size='340' side='right'caption='[[3u6w]], [[Resolution|resolution]] 2.21Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3u6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U6W FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KIV:3-METHYL-2-OXOBUTANOIC+ACID'>KIV</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u6w OCA], [https://pdbe.org/3u6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u6w RCSB], [https://www.ebi.ac.uk/pdbsum/3u6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u6w ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LEU1_MYCTU LEU1_MYCTU] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[2-isopropylmalate synthase 3D structures|2-isopropylmalate synthase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Baker EN]] | ||
| + | [[Category: Koon N]] | ||
| + | [[Category: Squire CJ]] | ||
Current revision
Truncated M. tuberculosis LeuA (1-425) complexed with KIV
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