1jlx
From Proteopedia
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| - | [[Image:1jlx.gif|left|200px]]<br /><applet load="1jlx" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1jlx, resolution 2.2Å" /> | ||
| - | '''AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE'''<br /> | ||
| - | == | + | ==AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE== |
| - | Amaranthus caudatus agglutinin contains a novel arrangement of four | + | <StructureSection load='1jlx' size='340' side='right'caption='[[1jlx]], [[Resolution|resolution]] 2.20Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1jlx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JLX FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MBN:TOLUENE'>MBN</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jlx OCA], [https://pdbe.org/1jlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jlx RCSB], [https://www.ebi.ac.uk/pdbsum/1jlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jlx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q71QF2_AMACA Q71QF2_AMACA] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars. | ||
| - | + | Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.,Transue TR, Smith AK, Mo H, Goldstein IJ, Saper MA Nat Struct Biol. 1997 Oct;4(10):779-83. PMID:9334739<ref>PMID:9334739</ref> | |
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| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 1jlx" style="background-color:#fffaf0;"></div> | |
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| - | + | ==See Also== | |
| + | *[[Agglutinin 3D structures|Agglutinin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Amaranthus caudatus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Goldstein IJ]] | ||
| + | [[Category: Mo H]] | ||
| + | [[Category: Saper MA]] | ||
| + | [[Category: Smith AK]] | ||
| + | [[Category: Transue TR]] | ||
Current revision
AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE
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