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3tsi

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[[Image:3tsi.png|left|200px]]
 
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==Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain==
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The line below this paragraph, containing "STRUCTURE_3tsi", creates the "Structure Box" on the page.
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<StructureSection load='3tsi' size='340' side='right'caption='[[3tsi]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tsi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Simian_virus_5_(strain_W3) Simian virus 5 (strain W3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSI FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.651&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsi OCA], [https://pdbe.org/3tsi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsi RCSB], [https://www.ebi.ac.uk/pdbsum/3tsi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsi ProSAT]</span></td></tr>
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{{STRUCTURE_3tsi| PDB=3tsi | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HN_PIV5 HN_PIV5] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
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===Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain===
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==See Also==
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*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_21994464}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21994464 is the PubMed ID number.
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[[Category: Bose S]]
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[[Category: Jardetzky TS]]
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{{ABSTRACT_PUBMED_21994464}}
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[[Category: Kors CA]]
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[[Category: Lamb RA]]
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==About this Structure==
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[[Category: Welch BD]]
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[[3tsi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Parainfluenza_virus_5 Parainfluenza virus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSI OCA].
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[[Category: Yuan P]]
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==Reference==
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<ref group="xtra">PMID:021994464</ref><references group="xtra"/>
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[[Category: Exo-alpha-sialidase]]
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[[Category: Parainfluenza virus 5]]
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[[Category: Bose, S.]]
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[[Category: Jardetzky, T S.]]
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[[Category: Kors, C A.]]
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[[Category: Lamb, R A.]]
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[[Category: Welch, B D.]]
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[[Category: Yuan, P.]]
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[[Category: 11-mer hydrophobic repeat]]
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[[Category: Ectodomain]]
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[[Category: Four stranded coiled coil]]
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[[Category: Four-helix bundle]]
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[[Category: Receptor binding protein]]
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[[Category: Viral protein]]
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Current revision

Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain

PDB ID 3tsi

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