2yj0

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[[Image:2yj0.png|left|200px]]
 
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==X-ray structure of chemically engineered Mycobacterium tuberculosis Dodecin==
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The line below this paragraph, containing "STRUCTURE_2yj0", creates the "Structure Box" on the page.
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<StructureSection load='2yj0' size='340' side='right'caption='[[2yj0]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2yj0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YJ0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=420:N-[2-({[5-(DIMETHYLAMINO)NAPHTHALEN-1-YL]SULFONYL}AMINO)ETHYL]-2-IODOACETAMIDE'>420</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2yj0| PDB=2yj0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yj0 OCA], [https://pdbe.org/2yj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yj0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yj0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8VK10_MYCTO Q8VK10_MYCTO]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The suitability for chemical engineering of the highly symmetrical Mycobacterium tuberculosis dodecin was investigated, its inner cavity providing a large compartment shields introduced compounds from bulk solvent. Hybrids were obtained by S-alkylation of cysteine mutants and characterized by spectroscopic methods, including the crystal structures of wild type and biohybrid dodecins.
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===X-RAY STRUCTURE OF CHEMICALLY ENGINEERED MYCOBACTERIUM TUBERCULOSIS DODECIN===
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Chemical engineering of Mycobacterium tuberculosis dodecin hybrids.,Vinzenz X, Grosse W, Linne U, Meissner B, Essen LO Chem Commun (Camb). 2011 Oct 21;47(39):11071-3. Epub 2011 Sep 6. PMID:21897938<ref>PMID:21897938</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2yj0" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21897938 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21897938}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[2yj0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJ0 OCA].
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Essen L-O]]
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==Reference==
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[[Category: Grosse W]]
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<ref group="xtra">PMID:021897938</ref><references group="xtra"/>
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[[Category: Linne U]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Meissner B]]
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[[Category: Essen, L O.]]
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[[Category: Vinzenz X]]
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[[Category: Grosse, W.]]
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[[Category: Linne, U.]]
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[[Category: Meissner, B.]]
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[[Category: Vinzenz, X.]]
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[[Category: Dodecin hybrid]]
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[[Category: Flavin binding protein]]
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[[Category: Flavoprotein]]
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[[Category: Protein-engineering]]
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[[Category: Putative storage protein]]
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Current revision

X-ray structure of chemically engineered Mycobacterium tuberculosis Dodecin

PDB ID 2yj0

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