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1o9l
From Proteopedia
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| - | [[Image:1o9l.gif|left|200px]]<br /><applet load="1o9l" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1o9l, resolution 2.40Å" /> | ||
| - | '''SUCCINATE:COENZYME-A TRANSFERASE (PIG HEART)'''<br /> | ||
| - | == | + | ==Succinate:Coenzyme-A Transferase (pig heart)== |
| - | + | <StructureSection load='1o9l' size='340' side='right'caption='[[1o9l]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[Category: | + | <table><tr><td colspan='2'>[[1o9l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O9L FirstGlance]. <br> |
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene>, <scene name='pdbligand=EMT:2-(ETHYLMERCURI-THIO)-BENZOIC+ACID'>EMT</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9l OCA], [https://pdbe.org/1o9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o9l RCSB], [https://www.ebi.ac.uk/pdbsum/1o9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SCOT1_PIG SCOT1_PIG] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o9/1o9l_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o9l ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Lewis | + | [[Category: Lewis G]] |
| - | [[Category: Lloyd | + | [[Category: Lloyd AJ]] |
| - | [[Category: Mitchell | + | [[Category: Mitchell EP]] |
| - | [[Category: Shoolingin-Jordan | + | [[Category: Shoolingin-Jordan P]] |
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Current revision
Succinate:Coenzyme-A Transferase (pig heart)
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