This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3tsn
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3tsn.png|left|200px]] | ||
| - | + | ==4-hydroxythreonine-4-phosphate dehydrogenase from Campylobacter jejuni== | |
| - | + | <StructureSection load='3tsn' size='340' side='right'caption='[[3tsn]], [[Resolution|resolution]] 2.63Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3tsn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cj1239, pdxA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192222 CAMJE])</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/4-hydroxythreonine-4-phosphate_dehydrogenase 4-hydroxythreonine-4-phosphate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.262 1.1.1.262] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsn OCA], [https://pdbe.org/3tsn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsn RCSB], [https://www.ebi.ac.uk/pdbsum/3tsn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsn ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | == | + | [[https://www.uniprot.org/uniprot/PDXA_CAMJE PDXA_CAMJE]] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).[HAMAP-Rule:MF_00536] |
| - | [[3tsn]] is a 4 chain structure with sequence from [ | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: 4-hydroxythreonine-4-phosphate dehydrogenase]] | [[Category: 4-hydroxythreonine-4-phosphate dehydrogenase]] | ||
| - | [[Category: | + | [[Category: Camje]] |
| - | [[Category: Anderson, W F | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Anderson, W F]] |
| - | [[Category: Gu, M | + | [[Category: Structural genomic]] |
| - | [[Category: Joachimiak, A | + | [[Category: Gu, M]] |
| - | [[Category: Kwon, K | + | [[Category: Joachimiak, A]] |
| - | [[Category: Osipiuk, J | + | [[Category: Kwon, K]] |
| - | + | [[Category: Osipiuk, J]] | |
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Structural genomic]] | ||
Current revision
4-hydroxythreonine-4-phosphate dehydrogenase from Campylobacter jejuni
| |||||||||||
