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3tsv

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[[Image:3tsv.png|left|200px]]
 
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==crystal structure of the third PDZ domain of the human ZO-1 MAGUK protein==
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The line below this paragraph, containing "STRUCTURE_3tsv", creates the "Structure Box" on the page.
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<StructureSection load='3tsv' size='340' side='right'caption='[[3tsv]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tsv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TSV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.989&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tsv OCA], [https://pdbe.org/3tsv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tsv RCSB], [https://www.ebi.ac.uk/pdbsum/3tsv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tsv ProSAT]</span></td></tr>
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{{STRUCTURE_3tsv| PDB=3tsv | SCENE= }}
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</table>
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== Function ==
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===crystal structure of the third PDZ domain of the human ZO-1 MAGUK protein===
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[https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3tsv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TSV OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Lavie, A.]]
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[[Category: Large Structures]]
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[[Category: Nomme, J.]]
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[[Category: Lavie A]]
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[[Category: Cell adhesion]]
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[[Category: Nomme J]]
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[[Category: Jam]]
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[[Category: Pdz]]
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[[Category: Scaffolding]]
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[[Category: Tight junction]]
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Current revision

crystal structure of the third PDZ domain of the human ZO-1 MAGUK protein

PDB ID 3tsv

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