3pwe

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[[Image:3pwe.png|left|200px]]
 
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==Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution==
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The line below this paragraph, containing "STRUCTURE_3pwe", creates the "Structure Box" on the page.
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<StructureSection load='3pwe' size='340' side='right'caption='[[3pwe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PWE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.199&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwe OCA], [https://pdbe.org/3pwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pwe RCSB], [https://www.ebi.ac.uk/pdbsum/3pwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwe ProSAT]</span></td></tr>
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{{STRUCTURE_3pwe| PDB=3pwe | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.
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===Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_21971175}}, adds the Publication Abstract to the page
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[[Category: Escherichia coli K-12]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21971175 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Bloom LB]]
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{{ABSTRACT_PUBMED_21971175}}
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[[Category: Marzahn MR]]
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[[Category: McKenna R]]
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==About this Structure==
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[[Category: Robbins AH]]
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[[3pwe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWE OCA].
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==Reference==
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<ref group="xtra">PMID:021971175</ref><references group="xtra"/>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Escherichia coli]]
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[[Category: Bloom, L B.]]
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[[Category: Marzahn, M R.]]
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[[Category: McKenna, R.]]
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[[Category: Robbins, A H.]]
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[[Category: Dna polymerase beta subunit mutant]]
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[[Category: Dna replication]]
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[[Category: Processivity factor]]
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[[Category: Sliding clamp]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution

PDB ID 3pwe

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