3q5w
From Proteopedia
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- | [[Image:3q5w.png|left|200px]] | ||
- | + | ==Structure of proteasome tether== | |
- | + | <StructureSection load='3q5w' size='340' side='right'caption='[[3q5w]], [[Resolution|resolution]] 2.75Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[3q5w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5W FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5w OCA], [https://pdbe.org/3q5w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5w RCSB], [https://www.ebi.ac.uk/pdbsum/3q5w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5w ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/CUT8_SCHPO CUT8_SCHPO] Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins like mitotic cyclin and cut2. Required for normal progression of anaphase.<ref>PMID:11084332</ref> <ref>PMID:16096059</ref> <ref>PMID:8065367</ref> | |
- | + | == References == | |
- | == | + | <references/> |
- | [[3q5w]] is a 2 chain structure with sequence from [ | + | __TOC__ |
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
- | [[Category: Schumacher | + | [[Category: Schumacher MA]] |
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Current revision
Structure of proteasome tether
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