3tz3
From Proteopedia
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| - | [[Image:3tz3.png|left|200px]]  | ||
| - | + | ==Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 2==  | |
| - | + | <StructureSection load='3tz3' size='340' side='right'caption='[[3tz3]], [[Resolution|resolution]] 2.70Å' scene=''>  | |
| - | + | == Structural highlights ==  | |
| - | + | <table><tr><td colspan='2'>[[3tz3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TZ3 FirstGlance]. <br>  | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr>  | |
| - | -->  | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B36:6-{[1-(ANTHRACEN-9-YLCARBONYL)PIPERIDIN-4-YL]METHYL}-2-METHYLQUINOLINE'>B36</scene></td></tr>  | 
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tz3 OCA], [https://pdbe.org/3tz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3tz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tz3 ProSAT]</span></td></tr>  | |
| + | </table>  | ||
| + | == Function ==  | ||
| + | [https://www.uniprot.org/uniprot/ACAC_YEAST ACAC_YEAST] Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.<ref>PMID:6108218</ref> <ref>PMID:6103540</ref> <ref>PMID:8943372</ref> <ref>PMID:10757783</ref> <ref>PMID:12730220</ref>   | ||
| - | ==  | + | ==See Also==  | 
| - | + | *[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]  | |
| - | + | == References ==  | |
| - | + | <references/>  | |
| - | + | __TOC__  | |
| - | + | </StructureSection>  | |
| - | + | [[Category: Large Structures]]  | |
| - | + | [[Category: Saccharomyces cerevisiae S288C]]  | |
| - | + | [[Category: Anderson MD]]  | |
| - | + | [[Category: Corbett JW]]  | |
| - | + | [[Category: Dirico KJ]]  | |
| - | + | [[Category: Harwood JH]]  | |
| - | ==  | + | [[Category: Landro JA]]  | 
| - | <  | + | [[Category: Marr E]]  | 
| - | [[Category: Saccharomyces cerevisiae   | + | [[Category: Rajamohan F]]  | 
| - | [[Category: Anderson  | + | [[Category: Reyes A]]  | 
| - | [[Category: Corbett  | + | [[Category: Tu M]]  | 
| - | [[Category: Dirico  | + | [[Category: Vajdos FF]]  | 
| - | [[Category: Harwood  | + | |
| - | [[Category: Landro  | + | |
| - | [[Category: Marr  | + | |
| - | [[Category: Rajamohan  | + | |
| - | [[Category: Reyes  | + | |
| - | [[Category: Tu  | + | |
| - | [[Category: Vajdos  | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the humanized carboxyltransferase domain of yeast Acetyl-coA caroxylase in complex with compound 2
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