3gom

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[[Image:3gom.png|left|200px]]
 
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==Barium bound to the Holliday junction sequence d(TCGGCGCCGA)4==
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The line below this paragraph, containing "STRUCTURE_3gom", creates the "Structure Box" on the page.
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<StructureSection load='3gom' size='340' side='right'caption='[[3gom]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3gom]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GOM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene></td></tr>
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{{STRUCTURE_3gom| PDB=3gom | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gom OCA], [https://pdbe.org/3gom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gom RCSB], [https://www.ebi.ac.uk/pdbsum/3gom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gom ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We describe a crystal structure, at atomic resolution (1.1 A, 100 K), of a ruthenium polypyridyl complex bound to duplex DNA, in which one ligand acts as a wedge in the minor groove, resulting in the 51 degrees kinking of the double helix. The complex cation Lambda-[Ru(1,4,5,8-tetraazaphenanthrene)(2)(dipyridophenazine)](2+) crystallizes in a 11 ratio with the oligonucleotide d(TCGGCGCCGA) in the presence of barium ions. Each complex binds to one duplex by intercalation of the dipyridophenazine ligand and also by semiintercalation of one of the orthogonal tetraazaphenanthrene ligands into a second symmetrically equivalent duplex. The result is noncovalent cross-linking and marked kinking of DNA.
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===Barium bound to the Holliday junction sequence d(TCGGCGCCGA)4===
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Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand.,Hall JP, O'Sullivan K, Naseer A, Smith JA, Kelly JM, Cardin CJ Proc Natl Acad Sci U S A. 2011 Oct 3. PMID:21969542<ref>PMID:21969542</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_21969542}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3gom" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21969542 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21969542}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3gom]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOM OCA].
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[[Category: Cardin CJ]]
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[[Category: Naseer A]]
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==Reference==
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<ref group="xtra">PMID:021969542</ref><references group="xtra"/>
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[[Category: Cardin, C J.]]
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[[Category: Naseer, A.]]
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[[Category: Dna]]
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[[Category: Holliday junction structure]]
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Current revision

Barium bound to the Holliday junction sequence d(TCGGCGCCGA)4

PDB ID 3gom

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OCA

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