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3ud4
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The C92U mutant c-di-GMP-I riboswitch bound to GpA== |
| + | <StructureSection load='3ud4' size='340' side='right'caption='[[3ud4]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ud4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UD4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ud4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ud4 OCA], [https://pdbe.org/3ud4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ud4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ud4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ud4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |
| - | + | *[[Riboswitch 3D structures|Riboswitch 3D structures]] | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vibrio cholerae]] | ||
| + | [[Category: Smith KD]] | ||
| + | [[Category: Strobel SA]] | ||
Current revision
The C92U mutant c-di-GMP-I riboswitch bound to GpA
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