4a4p
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==crystal structure of the Sec7 domain from human cytohesin1== | |
| - | + | <StructureSection load='4a4p' size='340' side='right'caption='[[4a4p]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4a4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4p OCA], [https://pdbe.org/4a4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4p RCSB], [https://www.ebi.ac.uk/pdbsum/4a4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CYH1_HUMAN CYH1_HUMAN] Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.<ref>PMID:10652308</ref> <ref>PMID:9653114</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Biou V]] | ||
| + | [[Category: Cherfils J]] | ||
| + | [[Category: Thompson AW]] | ||
| + | [[Category: Zeeh JC]] | ||
Current revision
crystal structure of the Sec7 domain from human cytohesin1
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