3t5i

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[[Image:3t5i.jpg|left|200px]]
 
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==Structure of Fully modified farnesylated Rheb Peptide in complex with PDE6D==
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The line below this paragraph, containing "STRUCTURE_3t5i", creates the "Structure Box" on the page.
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<StructureSection load='3t5i' size='340' side='right'caption='[[3t5i]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3t5i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T5I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMT:O-METHYLCYSTEINE'>CMT</scene>, <scene name='pdbligand=FAR:FARNESYL'>FAR</scene></td></tr>
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{{STRUCTURE_3t5i| PDB=3t5i | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t5i OCA], [https://pdbe.org/3t5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t5i RCSB], [https://www.ebi.ac.uk/pdbsum/3t5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t5i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDE6D_HUMAN PDE6D_HUMAN] Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).
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===Structure of Fully modified farnesylated Rheb Peptide in complex with PDE6D===
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==See Also==
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22002721 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22002721}}
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==About this Structure==
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[[3t5i]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5I OCA].
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==Reference==
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<ref group="xtra">PMID:022002721</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Chen, Y X.]]
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[[Category: Large Structures]]
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[[Category: Ismail, S A.]]
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[[Category: Chen Y-X]]
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[[Category: Wittinghofer, A.]]
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[[Category: Ismail SA]]
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[[Category: Farnesyl]]
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[[Category: Wittinghofer A]]
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[[Category: Immunoglobulin-like beta sandwitch fold]]
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[[Category: Lipid binding protein]]
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[[Category: Prenyl]]
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[[Category: Rheb]]
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[[Category: Signaling protein]]
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Current revision

Structure of Fully modified farnesylated Rheb Peptide in complex with PDE6D

PDB ID 3t5i

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OCA

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