2pde

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[[Image:2pde.png|left|200px]]
 
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==THE HIGH RESOLUTION STRUCTURE OF THE PERIPHERAL SUBUNIT-BINDING DOMAIN OF DIHYDROLIPOAMIDE ACETYLTRANSFERASE FROM THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX OF BACILLUS STEAROTHERMOPHILUS==
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The line below this paragraph, containing "STRUCTURE_2pde", creates the "Structure Box" on the page.
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<StructureSection load='2pde' size='340' side='right'caption='[[2pde]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pde]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PDE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pde OCA], [https://pdbe.org/2pde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pde RCSB], [https://www.ebi.ac.uk/pdbsum/2pde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pde ProSAT]</span></td></tr>
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{{STRUCTURE_2pde| PDB=2pde | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ODP2_GEOSE ODP2_GEOSE] The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/2pde_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pde ConSurf].
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<div style="clear:both"></div>
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===THE HIGH RESOLUTION STRUCTURE OF THE PERIPHERAL SUBUNIT-BINDING DOMAIN OF DIHYDROLIPOAMIDE ACETYLTRANSFERASE FROM THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX OF BACILLUS STEAROTHERMOPHILUS===
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==See Also==
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*[[Dihydrolipoamide acetyltransferase 3D structures|Dihydrolipoamide acetyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8450544}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8450544 is the PubMed ID number.
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[[Category: Appella E]]
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[[Category: Brocklehurst SM]]
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{{ABSTRACT_PUBMED_8450544}}
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[[Category: Hipps DS]]
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[[Category: Kalia YN]]
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==About this Structure==
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[[Category: Perham RN]]
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[[2pde]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDE OCA].
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[[Category: Sakaguchi K]]
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==Reference==
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<ref group="xtra">PMID:008450544</ref><ref group="xtra">PMID:012217703</ref><ref group="xtra">PMID:015267926</ref><references group="xtra"/>
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[[Category: Dihydrolipoyl dehydrogenase]]
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[[Category: Appella, E.]]
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[[Category: Brocklehurst, S M.]]
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[[Category: Hipps, D S.]]
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[[Category: Kalia, Y N.]]
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[[Category: Perham, R N.]]
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[[Category: Sakaguchi, K.]]
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[[Category: Acyltransferase]]
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[[Category: Oxido-reductase]]
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[[Category: Transferase]]
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Current revision

THE HIGH RESOLUTION STRUCTURE OF THE PERIPHERAL SUBUNIT-BINDING DOMAIN OF DIHYDROLIPOAMIDE ACETYLTRANSFERASE FROM THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX OF BACILLUS STEAROTHERMOPHILUS

PDB ID 2pde

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OCA

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