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3qum

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[[Image:3qum.jpg|left|200px]]
 
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==Crystal structure of human prostate specific antigen (PSA) in Fab sandwich with a high affinity and a PCa selective antibody==
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The line below this paragraph, containing "STRUCTURE_3qum", creates the "Structure Box" on the page.
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<StructureSection load='3qum' size='340' side='right'caption='[[3qum]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qum]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QUM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
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{{STRUCTURE_3qum| PDB=3qum | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qum OCA], [https://pdbe.org/3qum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qum RCSB], [https://www.ebi.ac.uk/pdbsum/3qum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qum ProSAT]</span></td></tr>
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</table>
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===Crystal structure of human prostate specific antigen (PSA) in Fab sandwich with a high affinity and a PCa selective antibody===
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== Function ==
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[https://www.uniprot.org/uniprot/KLK3_HUMAN KLK3_HUMAN] Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_22037582}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 22037582 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22037582}}
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==About this Structure==
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[[3qum]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QUM OCA].
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==Reference==
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<ref group="xtra">PMID:022037582</ref><ref group="xtra">PMID:022019475</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Semenogelase]]
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[[Category: Ducancel F]]
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[[Category: Ducancel, F.]]
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[[Category: Michel S]]
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[[Category: Michel, S.]]
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[[Category: Muller BH]]
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[[Category: Muller, B H.]]
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[[Category: Stura EA]]
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[[Category: Stura, E A.]]
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[[Category: Immune system]]
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[[Category: Kallikrein fold]]
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[[Category: N-linked and o-linked glycosylation]]
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[[Category: Natural post-transductional modification]]
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[[Category: Negative regulation of angiogenesis]]
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[[Category: Prostate-specific antigen]]
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[[Category: Serine protease]]
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Current revision

Crystal structure of human prostate specific antigen (PSA) in Fab sandwich with a high affinity and a PCa selective antibody

PDB ID 3qum

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