2xu2
From Proteopedia
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- | [[Image:2xu2.png|left|200px]] | ||
- | < | + | ==Crystal Structure of the hypothetical protein PA4511 from Pseudomonas aeruginosa== |
- | + | <StructureSection load='2xu2' size='340' side='right'caption='[[2xu2]], [[Resolution|resolution]] 2.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2xu2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x5e 2x5e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XU2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu2 OCA], [https://pdbe.org/2xu2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xu2 RCSB], [https://www.ebi.ac.uk/pdbsum/2xu2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu2 ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PXPA3_PSEAE PXPA3_PSEAE] Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.[HAMAP-Rule:MF_00691] | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | The Scottish Structural Proteomics Facility was funded to develop a laboratory scale approach to high throughput structure determination. The effort was successful in that over 40 structures were determined. These structures and the methods harnessed to obtain them are reported here. This report reflects on the value of automation but also on the continued requirement for a high degree of scientific and technical expertise. The efficiency of the process poses challenges to the current paradigm of structural analysis and publication. In the 5 year period we published ten peer-reviewed papers reporting structural data arising from the pipeline. Nevertheless, the number of structures solved exceeded our ability to analyse and publish each new finding. By reporting the experimental details and depositing the structures we hope to maximize the impact of the project by allowing others to follow up the relevant biology. | ||
- | + | The Scottish Structural Proteomics Facility: targets, methods and outputs.,Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH J Struct Funct Genomics. 2010 Jun;11(2):167-80. Epub 2010 Apr 24. PMID:20419351<ref>PMID:20419351</ref> | |
- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | + | </div> | |
- | + | <div class="pdbe-citations 2xu2" style="background-color:#fffaf0;"></div> | |
- | + | == References == | |
- | + | <references/> | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | == | + | [[Category: Large Structures]] |
- | + | [[Category: Pseudomonas aeruginosa PAO1]] | |
- | + | [[Category: Carter LG]] | |
- | == | + | [[Category: Johnson KA]] |
- | < | + | [[Category: Liu H]] |
- | [[Category: Pseudomonas aeruginosa]] | + | [[Category: McMahon SA]] |
- | [[Category: Carter | + | [[Category: Naismith JH]] |
- | [[Category: Johnson | + | [[Category: Oke M]] |
- | [[Category: Liu | + | [[Category: White MF]] |
- | [[Category: | + | |
- | [[Category: Naismith | + | |
- | [[Category: Oke | + | |
- | [[Category: White | + | |
- | + |
Current revision
Crystal Structure of the hypothetical protein PA4511 from Pseudomonas aeruginosa
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