2pft

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m (Protected "2pft" [edit=sysop:move=sysop])
Current revision (09:09, 21 February 2024) (edit) (undo)
 
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[[Image:2pft.png|left|200px]]
 
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==The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst==
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The line below this paragraph, containing "STRUCTURE_2pft", creates the "Structure Box" on the page.
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<StructureSection load='2pft' size='340' side='right'caption='[[2pft]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pft]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFT FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pft OCA], [https://pdbe.org/2pft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pft RCSB], [https://www.ebi.ac.uk/pdbsum/2pft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pft ProSAT]</span></td></tr>
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{{STRUCTURE_2pft| PDB=2pft | SCENE= }}
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</table>
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== Function ==
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===The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst===
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[https://www.uniprot.org/uniprot/EXOC7_MOUSE EXOC7_MOUSE] Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development (By similarity).[UniProtKB:E7FC72]<ref>PMID:12687004</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_17583731}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 17583731 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pf/2pft_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_17583731}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pft ConSurf].
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[[2pft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFT OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:017583731</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Moore, B A.]]
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[[Category: Moore BA]]
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[[Category: Xu, Z.]]
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[[Category: Xu Z]]
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[[Category: Endocytosis-exocytosis complex]]
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[[Category: Helix-turn-helix]]
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Current revision

The Crystal Structure of Mouse Exo70 Reveals Unique Features of the Mammalian Exocyst

PDB ID 2pft

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OCA

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