2lle
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds== | |
| - | + | <StructureSection load='2lle' size='340' side='right'caption='[[2lle]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2lle]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lle OCA], [https://pdbe.org/2lle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lle RCSB], [https://www.ebi.ac.uk/pdbsum/2lle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lle ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013][https://www.uniprot.org/uniprot/CHEY_THEMA CHEY_THEMA] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermotoga maritima]] | ||
| + | [[Category: Coles M]] | ||
| + | [[Category: Eisenbeis S]] | ||
| + | [[Category: Hocker B]] | ||
| + | [[Category: Meiler J]] | ||
| + | [[Category: Proffitt W]] | ||
| + | [[Category: Truffault V]] | ||
Current revision
Computational design of an eight-stranded (beta/alpha)-barrel from fragments of different folds
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