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3tk3

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[[Image:3tk3.jpg|left|200px]]
 
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==Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole==
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The line below this paragraph, containing "STRUCTURE_3tk3", creates the "Structure Box" on the page.
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<StructureSection load='3tk3' size='340' side='right'caption='[[3tk3]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tk3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TK3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8001&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPZ:4-(4-CHLOROPHENYL)IMIDAZOLE'>CPZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_3tk3| PDB=3tk3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tk3 OCA], [https://pdbe.org/3tk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tk3 RCSB], [https://www.ebi.ac.uk/pdbsum/3tk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tk3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CP2B4_RABIT CP2B4_RABIT] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it has a unique preference for the 5,6-olefin.
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===Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole===
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==See Also==
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22051155 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22051155}}
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==About this Structure==
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[[3tk3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TK3 OCA].
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==Reference==
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<ref group="xtra">PMID:022051155</ref><ref group="xtra">PMID:016373351</ref><ref group="xtra">PMID:015100217</ref><ref group="xtra">PMID:014563924</ref><ref group="xtra">PMID:017887776</ref><ref group="xtra">PMID:019397311</ref><ref group="xtra">PMID:020815363</ref><ref group="xtra">PMID:020880847</ref><ref group="xtra">PMID:021510666</ref><references group="xtra"/>
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[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Unspecific monooxygenase]]
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[[Category: Gay SC]]
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[[Category: Gay, S C.]]
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[[Category: Halpert JR]]
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[[Category: Halpert, J R.]]
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[[Category: Jang HH]]
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[[Category: Jang, H H.]]
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[[Category: Stout CD]]
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[[Category: Stout, C D.]]
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[[Category: Wilderman PR]]
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[[Category: Wilderman, P R.]]
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[[Category: Zhang Q]]
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[[Category: Zhang, Q.]]
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[[Category: Cyp 2b4]]
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[[Category: Cyp lm2]]
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[[Category: Cytochrome p450 2b4]]
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[[Category: Membrane protein]]
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[[Category: Monooxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: P450]]
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Current revision

Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole

PDB ID 3tk3

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