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3vgz

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[[Image:3vgz.jpg|left|200px]]
 
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==Crystal structure of E. coli YncE==
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The line below this paragraph, containing "STRUCTURE_3vgz", creates the "Structure Box" on the page.
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<StructureSection load='3vgz' size='340' side='right'caption='[[3vgz]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3vgz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VGZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vh0|3vh0]]</div></td></tr>
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{{STRUCTURE_3vgz| PDB=3vgz | SCENE= }}
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yncE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vgz OCA], [https://pdbe.org/3vgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vgz RCSB], [https://www.ebi.ac.uk/pdbsum/3vgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vgz ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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beta-Propellers are widely utilized in nature as recognition modules. The well conserved beta-propeller fold exhibits a high degree of functional diversity, which is probably accomplished through variations in the surface properties of the proteins. Little is known about the interactions between beta-propeller proteins and nucleic acids. In the present study, it has been found that the bacterial beta-propeller protein YncE binds to DNA. Crystal structures of YncE in the free form and complexed with DNA revealed that the surface region of YncE corresponding to the `canonical' substrate-binding site forms essential contacts with DNA. A single DNA base within a single-stranded DNA region is trapped in the hydrophobic pocket located within the central channel of the beta-propeller protein. These data provide physical evidence for the DNA-binding ability of the previously uncharacterized YncE and also suggest that the `canonical' substrate-binding site may be commonly adapted to facilitate nucleic acid binding in a subset of beta-propeller proteins.
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===Crystal structure of E. coli YncE===
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Structural basis for the DNA-binding activity of the bacterial beta-propeller protein YncE.,Kagawa W, Sagawa T, Niki H, Kurumizaka H Acta Crystallogr D Biol Crystallogr. 2011 Dec;67(Pt 12):1045-53. Epub 2011, Nov 5. PMID:22120742<ref>PMID:22120742</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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[[3vgz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VGZ OCA].
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<div class="pdbe-citations 3vgz" style="background-color:#fffaf0;"></div>
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[[Category: Escherichia coli]]
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== References ==
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[[Category: Kagawa, W.]]
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<references/>
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[[Category: Kurumizaka, H.]]
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__TOC__
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[[Category: Niki, H.]]
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</StructureSection>
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[[Category: Sagawa, T.]]
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[[Category: Ecoli]]
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[[Category: Large Structures]]
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[[Category: Kagawa, W]]
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[[Category: Kurumizaka, H]]
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[[Category: Niki, H]]
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[[Category: Sagawa, T]]
[[Category: Beta-propeller]]
[[Category: Beta-propeller]]
[[Category: Protein binding]]
[[Category: Protein binding]]

Current revision

Crystal structure of E. coli YncE

PDB ID 3vgz

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