3pqc

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[[Image:3pqc.png|left|200px]]
 
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==Crystal structure of Thermotoga maritima ribosome biogenesis GTP-binding protein EngB (YsxC/YihA) in complex with GDP==
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The line below this paragraph, containing "STRUCTURE_3pqc", creates the "Structure Box" on the page.
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<StructureSection load='3pqc' size='340' side='right'caption='[[3pqc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pqc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PQC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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{{STRUCTURE_3pqc| PDB=3pqc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pqc OCA], [https://pdbe.org/3pqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pqc RCSB], [https://www.ebi.ac.uk/pdbsum/3pqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pqc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENGB_THEMA ENGB_THEMA] Necessary for normal cell division and for the maintenance of normal septation (By similarity).
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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YsxC belongs to the YihA family of TRAFAC class GTPases. The protein is involved in the biogenesis of ribosomes and is essential for the survival of a wide range of bacteria. Here, crystal structures of YsxC from Thermotoga maritima and its complex with GDP were determined at maximal resolutions of 2.3 and 1.9 A, respectively. Major structural differences are observed in the switch I region, which is disordered in the apo form but exists in both an `open' and a `closed' conformation in the GDP-bound state. A comparison with the structure of the GMPPNP-YsxC complex from Bacillus subtilis provides insights into the mechanism of conformational change in the switch I and II regions upon hydrolysis of GTP.
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===Crystal structure of Thermotoga maritima ribosome biogenesis GTP-binding protein EngB (YsxC/YihA) in complex with GDP===
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Structure of an essential GTPase, YsxC, from Thermotoga maritima.,Chan KH, Wong KB Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jun 1;67(Pt, 6):640-6. Epub 2011 May 24. PMID:21636901<ref>PMID:21636901</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_21636901}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3pqc" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21636901 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21636901}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3pqc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PQC OCA].
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==Reference==
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<ref group="xtra">PMID:021636901</ref><references group="xtra"/>
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Chan, K H.]]
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[[Category: Chan KH]]
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[[Category: Wong, K B.]]
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[[Category: Wong KB]]
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[[Category: Cell cycle]]
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[[Category: Gtp binding]]
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[[Category: Gtpase]]
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[[Category: Hydrolase]]
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[[Category: Rossmann fold]]
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Current revision

Crystal structure of Thermotoga maritima ribosome biogenesis GTP-binding protein EngB (YsxC/YihA) in complex with GDP

PDB ID 3pqc

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