3p9a
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==An atomic view of the nonameric small terminase subunit of Bacteriophage P22== | |
| + | <StructureSection load='3p9a' size='340' side='right'caption='[[3p9a]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3p9a]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P9A FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.755Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p9a OCA], [https://pdbe.org/3p9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p9a RCSB], [https://www.ebi.ac.uk/pdbsum/3p9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p9a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TERS_BPP22 TERS_BPP22] The terminase small subunit binds to the packaging initiation site and regulates the ATPase activity of the terminase large subunit. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer once the capsid is full (headful packaging). Once the capsid is packaged with the DNA, the terminase complex is substituted by neck proteins.<ref>PMID:18775728</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Terminase 3D Structures|Terminase 3D Structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Salmonella virus P22]] | ||
| + | [[Category: Bhardwaj A]] | ||
| + | [[Category: Cingolani G]] | ||
| + | [[Category: Roy A]] | ||
Current revision
An atomic view of the nonameric small terminase subunit of Bacteriophage P22
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