3t6a

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[[Image:3t6a.jpg|left|200px]]
 
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==Structure of the C-terminal domain of BCAR3==
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The line below this paragraph, containing "STRUCTURE_3t6a", creates the "Structure Box" on the page.
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<StructureSection load='3t6a' size='340' side='right'caption='[[3t6a]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3t6a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T6A FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POG:(20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL'>POG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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{{STRUCTURE_3t6a| PDB=3t6a | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t6a OCA], [https://pdbe.org/3t6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t6a RCSB], [https://www.ebi.ac.uk/pdbsum/3t6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t6a ProSAT]</span></td></tr>
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</table>
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===Structure of the C-terminal domain of BCAR3===
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== Function ==
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[https://www.uniprot.org/uniprot/BCAR3_HUMAN BCAR3_HUMAN] May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.<ref>PMID:9582273</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22081014 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22081014}}
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==About this Structure==
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[[3t6a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6A OCA].
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==Reference==
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<ref group="xtra">PMID:022081014</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Mace, P D.]]
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[[Category: Large Structures]]
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[[Category: Riedl, S J.]]
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[[Category: Mace PD]]
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[[Category: Robinson, H.]]
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[[Category: Riedl SJ]]
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[[Category: Cdc25-homology domain]]
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[[Category: Robinson H]]
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[[Category: Gtpase exchange factor]]
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[[Category: Signaling protein]]
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Current revision

Structure of the C-terminal domain of BCAR3

PDB ID 3t6a

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OCA

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