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2llk

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[[Image:2llk.jpg|left|200px]]
 
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==Solution NMR structure of the N-terminal myb-like 1 domain of the human cyclin-D-binding transcription factor 1 (hDMP1), Northeast Structural Genomics Consortium (NESG) target ID hr8011a==
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The line below this paragraph, containing "STRUCTURE_2llk", creates the "Structure Box" on the page.
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<StructureSection load='2llk' size='340' side='right'caption='[[2llk]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2llk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2llk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2llk OCA], [https://pdbe.org/2llk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2llk RCSB], [https://www.ebi.ac.uk/pdbsum/2llk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2llk ProSAT]</span></td></tr>
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{{STRUCTURE_2llk| PDB=2llk | SCENE= }}
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</table>
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== Function ==
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===Solution NMR structure of the N-terminal myb-like 1 domain of the human cyclin-D-binding transcription factor 1 (hDMP1), Northeast Structural Genomics Consortium (NESG) target ID hr8011a===
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[https://www.uniprot.org/uniprot/DMTF1_HUMAN DMTF1_HUMAN] Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.<ref>PMID:12917399</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2llk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLK OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Bellanda, M.]]
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[[Category: Arrowsmith C]]
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[[Category: Garcia, M.]]
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[[Category: Bellanda M]]
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[[Category: Houliston, S.]]
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[[Category: Garcia M]]
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[[Category: Lemak, A.]]
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[[Category: Houliston S]]
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[[Category: Min, J.]]
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[[Category: Lemak A]]
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[[Category: Montecchio, M.]]
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[[Category: Min J]]
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[[Category: Montelione, G T.]]
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[[Category: Montecchio M]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Xu C]]
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[[Category: Xu, C.]]
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[[Category: Yee A]]
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[[Category: Yee, A.]]
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[[Category: Cell cycle]]
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[[Category: Helix bundle]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
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[[Category: Transcription]]
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Current revision

Solution NMR structure of the N-terminal myb-like 1 domain of the human cyclin-D-binding transcription factor 1 (hDMP1), Northeast Structural Genomics Consortium (NESG) target ID hr8011a

PDB ID 2llk

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