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3src

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[[Image:3src.png|left|200px]]
 
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==Structure of Pseudomonas aeruginosa PvdQ bound to NS2028==
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The line below this paragraph, containing "STRUCTURE_3src", creates the "Structure Box" on the page.
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<StructureSection load='3src' size='340' side='right'caption='[[3src]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3src]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SRC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=28N:8-BROMO-4H-[1,2,4]OXADIAZOLO[3,4-C][1,4]BENZOXAZIN-1-ONE'>28N</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_3src| PDB=3src | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3src FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3src OCA], [https://pdbe.org/3src PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3src RCSB], [https://www.ebi.ac.uk/pdbsum/3src PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3src ProSAT]</span></td></tr>
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</table>
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===Structure of Pseudomonas aeruginosa PvdQ bound to NS2028===
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== Function ==
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[https://www.uniprot.org/uniprot/PVDQ_PSEAE PVDQ_PSEAE] Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length). Degrades 3-oxo-C12-HSL, one of the two main AHL signal molecules of P.aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum-sensing system. Therefore, may enable P.aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential. Also appears to be required for pyoverdin biosynthesis.<ref>PMID:16495538</ref> <ref>PMID:14532048</ref> <ref>PMID:12686626</ref>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21892836}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21892836 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21892836}}
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Drake EJ]]
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==About this Structure==
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[[Category: Gulick AM]]
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[[3src]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRC OCA].
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==Reference==
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<ref group="xtra">PMID:021892836</ref><references group="xtra"/>
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[[Category: Acyl-homoserine-lactone acylase]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Drake, E J.]]
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[[Category: Gulick, A M.]]
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[[Category: Acylase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Liganded]]
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[[Category: Nrps tailoring]]
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Current revision

Structure of Pseudomonas aeruginosa PvdQ bound to NS2028

PDB ID 3src

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