3tw8

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[[Image:3tw8.png|left|200px]]
 
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==GEF domain of DENND 1B in complex with Rab GTPase Rab35==
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The line below this paragraph, containing "STRUCTURE_3tw8", creates the "Structure Box" on the page.
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<StructureSection load='3tw8' size='340' side='right'caption='[[3tw8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tw8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TW8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tw8 OCA], [https://pdbe.org/3tw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tw8 RCSB], [https://www.ebi.ac.uk/pdbsum/3tw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tw8 ProSAT]</span></td></tr>
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{{STRUCTURE_3tw8| PDB=3tw8 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DEN1B_HUMAN DEN1B_HUMAN] Guanine nucleotide exchange factor (GEF) for RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. May play a role in clathrin-mediated endocytosis.<ref>PMID:20154091</ref> <ref>PMID:20937701</ref>
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===GEF domain of DENND 1B in complex with Rab GTPase Rab35===
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==See Also==
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
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== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 22065758 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_22065758}}
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==About this Structure==
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[[3tw8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TW8 OCA].
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==Reference==
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<ref group="xtra">PMID:022065758</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kummel, D.]]
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[[Category: Large Structures]]
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[[Category: Reinisch, K M.]]
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[[Category: Kummel D]]
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[[Category: Wu, X D.]]
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[[Category: Reinisch KM]]
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[[Category: Guanine exchange factor]]
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[[Category: Wu XD]]
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[[Category: Longin domain]]
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[[Category: Protein transport]]
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[[Category: Rab gtpase]]
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Current revision

GEF domain of DENND 1B in complex with Rab GTPase Rab35

PDB ID 3tw8

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