3qoa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:52, 14 March 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3qoa.png|left|200px]]
 
-
<!--
+
==Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine.==
-
The line below this paragraph, containing "STRUCTURE_3qoa", creates the "Structure Box" on the page.
+
<StructureSection load='3qoa' size='340' side='right'caption='[[3qoa]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3qoa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QOA FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3QO:4-BENZYLPYRIDINE'>3QO</scene>, <scene name='pdbligand=CM5:5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE'>CM5</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-
{{STRUCTURE_3qoa| PDB=3qoa | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qoa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qoa OCA], [https://pdbe.org/3qoa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qoa RCSB], [https://www.ebi.ac.uk/pdbsum/3qoa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qoa ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine.===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/CP2B6_HUMAN CP2B6_HUMAN] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.<ref>PMID:11695850</ref>
-
 
+
-
<!--
+
-
The line below this paragraph, {{ABSTRACT_PUBMED_21875942}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21875942 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21875942}}
+
-
 
+
-
==About this Structure==
+
-
[[3qoa]] is a 1 chain structure of [[Cytochrome P450]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QOA OCA].
+
==See Also==
==See Also==
-
*[[Cytochrome P450]]
+
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:021875942</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Unspecific monooxygenase]]
+
[[Category: Large Structures]]
-
[[Category: Halpert, J R.]]
+
[[Category: Halpert JR]]
-
[[Category: Pascual, J.]]
+
[[Category: Pascual J]]
-
[[Category: Shah, M B.]]
+
[[Category: Shah MB]]
-
[[Category: Stout, C D.]]
+
[[Category: Stout CD]]
-
[[Category: Cyp2b6]]
+
-
[[Category: Cytochrome p450 2b6]]
+
-
[[Category: Endoplasmic reticulum]]
+
-
[[Category: Heme]]
+
-
[[Category: Iron]]
+
-
[[Category: Membrane]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Metal binding]]
+
-
[[Category: Mircosome]]
+
-
[[Category: Monooxygenase]]
+
-
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+
-
[[Category: P450]]
+
-
[[Category: Phosphoprotein]]
+

Current revision

Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine.

PDB ID 3qoa

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3qoa"
Personal tools