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2wm5

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[[Image:2wm5.png|left|200px]]
 
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==X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124==
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The line below this paragraph, containing "STRUCTURE_2wm5", creates the "Structure Box" on the page.
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<StructureSection load='2wm5' size='340' side='right'caption='[[2wm5]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2wm5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WM5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WM5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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{{STRUCTURE_2wm5| PDB=2wm5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wm5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wm5 OCA], [https://pdbe.org/2wm5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wm5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wm5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wm5 ProSAT]</span></td></tr>
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</table>
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===X-RAY STRUCTURE OF THE SUBSTRATE-FREE MYCOBACTERIUM TUBERCULOSIS CYTOCHROME P450 CYP124===
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== Function ==
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[https://www.uniprot.org/uniprot/CP124_MYCTU CP124_MYCTU]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_19933331}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19933331 is the PubMed ID number.
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<jmolCheckbox>
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-->
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/2wm5_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19933331}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2wm5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WM5 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wm5 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:019933331</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Large Structures]]
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[[Category: Johnston, J B.]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Kells, P M.]]
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[[Category: Johnston JB]]
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[[Category: Montellano, P R.Ortiz De.]]
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[[Category: Kells PM]]
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[[Category: Podust, L M.]]
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[[Category: Ortiz de Montellano PR]]
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[[Category: Fatty acid]]
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[[Category: Podust LM]]
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[[Category: Heme]]
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[[Category: Iron]]
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[[Category: Metal-binding]]
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[[Category: Monooxygenase]]
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[[Category: Omega-hydroxylation]]
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[[Category: Oxidoreductase]]
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[[Category: P450]]
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Current revision

X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124

PDB ID 2wm5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

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