3tix

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[[Image:3tix.png|left|200px]]
 
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==Crystal structure of the Chp1-Tas3 complex core==
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The line below this paragraph, containing "STRUCTURE_3tix", creates the "Structure Box" on the page.
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<StructureSection load='3tix' size='340' side='right'caption='[[3tix]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tix]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TIX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9001&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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{{STRUCTURE_3tix| PDB=3tix | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tix OCA], [https://pdbe.org/3tix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tix RCSB], [https://www.ebi.ac.uk/pdbsum/3tix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tix ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the Chp1-Tas3 complex core===
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== Function ==
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[https://www.uniprot.org/uniprot/TAS3_SCHPO TAS3_SCHPO] Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-induced transcriptional silencing (RITS) complex which is involved in the biosynthesis of dsRNA from primer siRNAs provided by the RNA-directed RNA polymerase (RDRC) complex.<ref>PMID:15607976</ref> <ref>PMID:14704433</ref> [https://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST] Not known; suppressor of MIF2 mutations.
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22081013 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22081013}}
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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==About this Structure==
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[[Category: Joshua-Tor L]]
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[[3tix]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae,_schizosaccharomyces_pombe Saccharomyces cerevisiae, schizosaccharomyces pombe] and [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TIX OCA].
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[[Category: Schalch T]]
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==Reference==
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<ref group="xtra">PMID:022081013</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae, schizosaccharomyces pombe]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Joshua-Tor, L.]]
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[[Category: Schalch, T.]]
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[[Category: Alpha-helical hairpin]]
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[[Category: Argonaute]]
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[[Category: Clrc]]
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[[Category: Gene regulation-protein binding complex]]
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[[Category: Heterochromatin]]
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[[Category: Nucleus]]
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[[Category: Pin]]
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[[Category: Rdrc]]
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[[Category: Rit]]
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[[Category: Rnai]]
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[[Category: Rossmann fold]]
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[[Category: Silencing]]
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[[Category: Spoc]]
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Current revision

Crystal structure of the Chp1-Tas3 complex core

PDB ID 3tix

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