3tu4

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[[Image:3tu4.png|left|200px]]
 
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==Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle.==
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The line below this paragraph, containing "STRUCTURE_3tu4", creates the "Structure Box" on the page.
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<StructureSection load='3tu4' size='340' side='right'caption='[[3tu4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tu4]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TU4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tu4 OCA], [https://pdbe.org/3tu4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tu4 RCSB], [https://www.ebi.ac.uk/pdbsum/3tu4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tu4 ProSAT]</span></td></tr>
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{{STRUCTURE_3tu4| PDB=3tu4 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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===Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle.===
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==See Also==
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*[[Histone 3D structures|Histone 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22096199 is the PubMed ID number.
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[[Category: Saccharomyces cerevisiae S288C]]
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{{ABSTRACT_PUBMED_22096199}}
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==About this Structure==
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[[3tu4]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c] and [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TU4 OCA].
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==Reference==
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<ref group="xtra">PMID:022096199</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Xenopus laevis]]
[[Category: Xenopus laevis]]
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[[Category: Armache, K J.]]
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[[Category: Armache K-J]]
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[[Category: Canzio, D.]]
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[[Category: Canzio D]]
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[[Category: Garlick, J D.]]
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[[Category: Garlick JD]]
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[[Category: Kingston, R E.]]
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[[Category: Kingston RE]]
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[[Category: Narlikar, G J.]]
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[[Category: Narlikar GJ]]
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[[Category: Gene silencing]]
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[[Category: Histone]]
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[[Category: Nucleosome]]
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[[Category: Signaling protein-structural protein-dna complex]]
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Current revision

Crystal structure of the Sir3 BAH domain in complex with a nucleosome core particle.

PDB ID 3tu4

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OCA

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