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3utd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Ec_IspH in complex with 4-oxopentyl diphosphate== | |
| + | <StructureSection load='3utd' size='340' side='right'caption='[[3utd]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3utd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UTD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CJ:4-OXOPENTYL+TRIHYDROGEN+DIPHOSPHATE'>0CJ</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3utd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3utd OCA], [https://pdbe.org/3utd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3utd RCSB], [https://www.ebi.ac.uk/pdbsum/3utd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3utd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bacher A]] | ||
| + | [[Category: Eisenreich W]] | ||
| + | [[Category: Groll M]] | ||
| + | [[Category: Oldfield E]] | ||
| + | [[Category: Schulz C]] | ||
| + | [[Category: Span I]] | ||
| + | [[Category: Wang K]] | ||
| + | [[Category: Wang W]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Ec_IspH in complex with 4-oxopentyl diphosphate
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Categories: Escherichia coli K-12 | Large Structures | Bacher A | Eisenreich W | Groll M | Oldfield E | Schulz C | Span I | Wang K | Wang W | Zhang Y
