3uv6
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3uv6 is ON HOLD Authors: Span, I., Wang, K., Wang, W., Zhang, Y., Bacher, A., Eisenreich, W., Schulz, C., Oldfield, E., Groll, M. Description: Ec_I...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)== | |
| + | <StructureSection load='3uv6' size='340' side='right'caption='[[3uv6]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3uv6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UV6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CH:4-HYDROXYBUTYL+TRIHYDROGEN+DIPHOSPHATE'>0CH</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uv6 OCA], [https://pdbe.org/3uv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uv6 RCSB], [https://www.ebi.ac.uk/pdbsum/3uv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uv6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bacher A]] | ||
| + | [[Category: Eisenreich W]] | ||
| + | [[Category: Groll M]] | ||
| + | [[Category: Oldfield E]] | ||
| + | [[Category: Schulz C]] | ||
| + | [[Category: Span I]] | ||
| + | [[Category: Wang K]] | ||
| + | [[Category: Wang W]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)
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Categories: Escherichia coli K-12 | Large Structures | Bacher A | Eisenreich W | Groll M | Oldfield E | Schulz C | Span I | Wang K | Wang W | Zhang Y
