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3td1

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[[Image:3td1.jpg|left|200px]]
 
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==Crystal structure of the bacterial A1408G-mutant and the protozoa cytoplasmic ribosomal decoding site in complex with geneticin==
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The line below this paragraph, containing "STRUCTURE_3td1", creates the "Structure Box" on the page.
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<StructureSection load='3td1' size='340' side='right'caption='[[3td1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3td1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TD1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5BU:5-BROMO-URIDINE-5-MONOPHOSPHATE'>5BU</scene>, <scene name='pdbligand=GET:GENETICIN'>GET</scene></td></tr>
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{{STRUCTURE_3td1| PDB=3td1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3td1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3td1 OCA], [https://pdbe.org/3td1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3td1 RCSB], [https://www.ebi.ac.uk/pdbsum/3td1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3td1 ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Resistance explained: The crystal structures of the ribosomal decoding A site with an A1408G antibiotic-resistance mutation were solved in the presence and absence of the aminoglycoside geneticin (see structure, geneticin carbon framework in yellow). These structures show how bacteria acquire high-level resistance against aminoglycosides by the mutation.
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===Crystal structure of the bacterial A1408G-mutant and the protozoa cytoplasmic ribosomal decoding site in complex with geneticin===
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A Structural Basis for the Antibiotic Resistance Conferred by an A1408G Mutation in 16S rRNA and for the Antiprotozoal Activity of Aminoglycosides.,Kondo J Angew Chem Int Ed Engl. 2011 Nov 23. doi: 10.1002/anie.201106084. PMID:22110016<ref>PMID:22110016</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_22110016}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3td1" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 22110016 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_22110016}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3td1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TD1 OCA].
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[[Category: Kondo J]]
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==Reference==
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<ref group="xtra">PMID:022110016</ref><references group="xtra"/>
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[[Category: Kondo, J.]]
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[[Category: Decoding]]
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[[Category: Ribosome]]
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[[Category: Rna-antibiotic complex]]
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Current revision

Crystal structure of the bacterial A1408G-mutant and the protozoa cytoplasmic ribosomal decoding site in complex with geneticin

PDB ID 3td1

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