3tgn

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[[Image:3tgn.png|left|200px]]
 
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==Crystal Structure of the zinc-dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-bound State==
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The line below this paragraph, containing "STRUCTURE_3tgn", creates the "Structure Box" on the page.
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<StructureSection load='3tgn' size='340' side='right'caption='[[3tgn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tgn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_D39 Streptococcus pneumoniae D39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TGN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3tgn| PDB=3tgn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tgn OCA], [https://pdbe.org/3tgn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tgn RCSB], [https://www.ebi.ac.uk/pdbsum/3tgn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tgn ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of the zinc-dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-bound State===
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== Function ==
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[https://www.uniprot.org/uniprot/ADCR_STRP2 ADCR_STRP2] Zinc-responsive regulator that acts both as a repressor and as an activator by regulating directly the promoters of its target genes. In the presence of zinc, directly represses the expression of the adcRCBA operon, of genes coding for a group of surface antigen zinc-binding pneumococcal histidine triad proteins (PhtA, PhtB, PhtD and PhtE), and of adcAII. Can also activate expression of adh.<ref>PMID:20804771</ref> <ref>PMID:21603707</ref>
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22085181 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22085181}}
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[[Category: Streptococcus pneumoniae D39]]
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[[Category: Dann III CE]]
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==About this Structure==
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[[Category: Giedroc DP]]
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[[3tgn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGN OCA].
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[[Category: Guerra AJ]]
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==Reference==
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<ref group="xtra">PMID:022085181</ref><references group="xtra"/>
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[[Category: Streptococcus pneumoniae]]
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[[Category: Giedroc, D P.]]
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[[Category: Guerra, A J.]]
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[[Category: III, C E.Dann.]]
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[[Category: Helix-turn-helix]]
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[[Category: Transcription]]
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[[Category: Transcriptional regulator]]
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Current revision

Crystal Structure of the zinc-dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-bound State

PDB ID 3tgn

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