3kom

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[[Image:3kom.png|left|200px]]
 
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==Crystal structure of apo transketolase from Francisella tularensis==
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The line below this paragraph, containing "STRUCTURE_3kom", creates the "Structure Box" on the page.
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<StructureSection load='3kom' size='340' side='right'caption='[[3kom]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3kom]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fratt Fratt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KOM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tktA, FTT1369c, FTT_1369c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td></tr>
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{{STRUCTURE_3kom| PDB=3kom | SCENE= }}
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kom OCA], [https://pdbe.org/3kom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kom RCSB], [https://www.ebi.ac.uk/pdbsum/3kom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kom ProSAT]</span></td></tr>
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===Crystal structure of apo transketolase from Francisella tularensis===
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/Q5NF74_FRATT Q5NF74_FRATT]] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).[RuleBase:RU004996]
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==About this Structure==
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== Evolutionary Conservation ==
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[[3kom]] is a 2 chain structure of [[Transketolase]] with sequence from [http://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis Francisella tularensis subsp. tularensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOM OCA].
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/3kom_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kom ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Transketolase]]
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*[[Transketolase|Transketolase]]
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[[Category: Francisella tularensis subsp. tularensis]]
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__TOC__
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</StructureSection>
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[[Category: Fratt]]
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[[Category: Large Structures]]
[[Category: Transketolase]]
[[Category: Transketolase]]
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[[Category: Anderson, S M.]]
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[[Category: Anderson, S M]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Gordon, E.]]
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[[Category: Gordon, E]]
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[[Category: Kwon, K.]]
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[[Category: Kwon, K]]
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[[Category: Savchenko, A.]]
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[[Category: Savchenko, A]]
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[[Category: Skarina, T.]]
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[[Category: Skarina, T]]
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[[Category: Wawrzak, Z.]]
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[[Category: Wawrzak, Z]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Transketolase]]
 

Current revision

Crystal structure of apo transketolase from Francisella tularensis

PDB ID 3kom

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